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Data on their alcohol consumption were obtained by interview. Group S comprised 78 patients 67 men and 11 women with mean age of 53 years, range 23—85 years AST Adv! 2000 alcohol abuse or dependence, admitted to surgical or medical wards, with a wide range of different somatic S diseases e.


These diagnoses are by themselves not expected to give increased serum aminotransferase levels. As AST Adv! 2000 the diagnosis of alcohol abuse or dependence, we had to rely upon the diagnosis made by the treating physician, in view of the retrospective AST Adv! 2000 of this study. Group C comprised 48 patients 35 men and 13 women with mean age 58 years, range 40—81 admitted to surgical or medical wards for treatment of complications of alcohol-related liver cirrhosis C.

The De Ritis Ratio: The Test of Time

Included were only those patients in whom the diagnosis of cirrhosis was based on liver biopsy or the presence of oesophageal varices or ascites. In Groups S and C, we were AST Adv! 2000 able to obtain information regarding the consumed amounts of alcohol, in view of the retrospective nature of this study.

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In Group W, blood samples for determination of liver function were collected in the morning, the day after admission and before start of medication for withdrawal symptoms. Data on patients in Groups S AST Adv! 2000 C were collected consecutively from the cohort of patients hospitalized during — The first time treatment in this period was chosen.

Association of Surgical Technologists

The laboratory tests as AST Adv! 2000 as the questioning of the patients about alcohol consumption were part of the routine clinical assessment of the patients. Thus, this study was considered as a clinical quality control study.


Since the data were put into data files in an unidentified status, no ethical permission was considered necessary. Standard laboratory methods were used for the laboratory analyses.

The De Ritis Ratio: The Test of Time

Enzymat; CDT: FPLC Jeppsson et al. The ratio was midway between in the S group.

AST Adv! 2000 1. No literary matter in The Clinical Biochemist — Reviews is to be reproduced, stored in a retrieval system or transmitted in any form by electronic or mechanical means, photocopying or recording, without permission.

Requests AST Adv! 2000 do so should be addressed to the Editor. While initially described as a characteristic of acute viral hepatitis where ALT was usually higher than AST, other authors have subsequently found it useful in alcoholic hepatitis, where AST is usually higher than ALT.

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These interpretations are far too simplistic however as acute viral hepatitis can have AST greater than ALT, and this can be a sign of fulminant disease, while alcoholic hepatitis can have ALT greater than AST when several days have elapsed since alcohol exposure. The ratio therefore represents the time course and aggressiveness of disease that would be predicted from the relatively short half-life of AST 18 h compared to ALT 36 h. AST Adv! 2000 are methodological issues, particularly whether or not pyridoxal phosphate is used in the transaminase assays, and although this can have specific effects when patient samples are deficient in this vitamin, these method differences generally have mild effects on the usefulness of the assays or the ratio.


The ratio of the serum activities of AST and ALT was first described by . but a high AST/ALT ratio is suggestive of either recent exposure or AST Adv! 2000 alcoholic. TXT, SOFTWARE BULLETIN #B,AST-VGA PLUS UTILITIES TXT, SOFTWARE BULLETIN #,Server Advanced Diags, Version .


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